Yadda Yawan Cin Abinci ke Canza Kwakwalwa

Shin kuna mamakin idan kek ɗin wannan rana zai canza jikin ku? Yayinda yawancin mu ke tunanin zai canza layin mu, 'yan mamaki ko shima yana canza kwakwalwa. Amma yana yi, kuma binciken da aka buga kwanan nan (Rossi, 2019) ya nuna mana yadda.

Tunanin cewa kwakwalwa tana shafar kusan duk abin da muke yi bai kamata ya zama abin mamaki ba; wanda muke so, yadda muke ji, har ma abin da muke ci yana shafar aikin kwakwalwa. Kwance mai zurfi a gindin kwakwalwarmu yana rayuwa rukunin sel waɗanda suka ƙunshi hypothalamus. The hypothalamus orchestrates iko a kan da dama halaye alaka da rayuwa na jinsin; dabi'un da, kamar yadda na saba gaya wa ɗalibina, sun ƙunshi F guda huɗu na ka'idar hypothalamic - faɗa, gudu, ciyarwa, da saduwa.

Kamar yawancin yankuna na kwakwalwa, ana raba hypothalamus zuwa ƙaramin tsari; waɗannan sau da yawa ana kiransu ta amfani da kalmomin da ke nuni zuwa alƙibla. Yi la'akari, alal misali, hypothalamus na gefe. Sunansa yana nuna cewa yana zaune a sashin gefe na hypothalamus, ko kuma daga tsakiya. Wadanda daga cikin mu masu sha'awar halayen motsa jiki sun san cewa yin nazarin tasirin kwakwalwa akan ciyar da ku babu makawa za ku ƙetare hanyoyi tare da hypothalamus na gefe. Wannan saboda tsarin yana da mahimmanci don sauƙaƙe ko ƙara cin abinci. Yana yin hakan ta hanyar daidaita metabolism, narkewa, ɓarkewar insulin, da ɗanɗano ɗanɗano, don suna wasu dalilai. Hakanan ana kiyaye hypothalamus na gefe sosai a cikin nau'ikan kuma don haka ya dace don yin ƙirar fannoni daban -daban na halayen cin ɗan adam. Don haka lokacin da kuke tunanin ƙara cin abinci, yi tunanin ƙara yawan aiki a cikin hypothalamus na gefe.

An fara tabbatar da wannan alaƙar a farkon binciken dabbobin da ba na ɗan adam ba, wanda ya nuna cewa berayen da ke lalata lalacewar hypothalamus na su sau da yawa sun ƙi cin abinci kuma, sabanin haka, kamar yadda mutum zai iya tsammanin, motsawa ko kunna wannan yankin ya haifar da cin abinci mara ƙoshin lafiya. Tun daga yanzu an yi nazari mai zurfi game da alaƙar da ke tsakanin cin abinci da hypothalamus na gefe kuma waɗannan cikakkun bayanai sun fi ƙarfin tattaunawar mu. Ka tabbata, duk da haka, ƙwararrun ƙwararrun masana ilimin halayyar ɗabi'a sun sadaukar da adadin sa'o'i marasa adadi don sanar da fahimtarmu game da yadda hypothalamus na gefe ke yin sulhu tsakanin cin abinci da ladan abinci. Labarin na Rossi da abokan aiki suna yin hakan, ta hanyar nuna yadda yawan cin abinci ke sake fasalin hypothalamus na gefe da yadda waɗannan canje -canjen ke shafar yadda muke cin abinci.

Ta hanyar haɗa dabaru iri-iri na salon salula, masu gwajin sun bincika ko abinci mai-mai mai yawa ya canza yanayin bayyanar sel a cikin hypothalamus na gefe. An tsara gwajin don kwatanta kwatancen ƙwayoyin sel a cikin beraye waɗanda ke karɓar abinci mai kitse da waɗanda ke karɓar abinci na yau da kullun. Sun gano canjin halittar da aka canza sakamakon kiba a cikin sel daban -daban a cikin hypothalamus na gefe. Koyaya, mafi girman canjin-haifar da canjin kwayoyin halitta ya faru a cikin sel wanda ke ɗauke da furotin da ake kira vesicular glutamate transporter type-2. Gabaɗaya, waɗannan sel suna amfani da sinadarin ƙwaƙwalwar ƙwaƙwalwa mai saurin motsa jiki mai suna glutamate. Sun sake bincika waɗannan sel kuma sun gano cewa suna mai da martani ga amfani da sukari; duk da haka, girman martanin ya dogara da yanayin motsawar dabbobi: Yawan abincin da dabbar ke so ta yi tasiri yadda ƙwayoyin ke amsa sukari.

Kafin ciyar da beraye (ƙarancin motsa jiki) ko gabatar da yanayin azumi na sa'o'i 24 (yanayin motsa jiki) kafin gwajin ya sarrafa motsa abinci. Kwayoyin motsa jiki a cikin hypothalamus na gefe na dabbobi a cikin ƙarancin motsa jiki (ba masu jin yunwa ba) sun sami babban aiki bayan cin sukari fiye da dabbobin da ke azumi. Wannan yana nuna cewa ƙoshin abinci yana tasiri lada mai lada don abincin da ke faruwa a cikin hypothalamus na gefe.

Abin da ya fi ban sha'awa game da bayanin lamba na waɗannan sel masu ban sha'awa shine cewa abinci mai-mai mai yawa shima ya canza adadin martanin su. Wato, ƙwayoyin dabbobin da ke cin abinci na yau da kullun suna kiyaye ikon su na gano yawan sukari, amma sel a cikin beraye a kan abincin mai-mai ya zama sannu a hankali ya kasa amsa sukari; haka, canjin kwakwalwa.

Waɗannan binciken sabon labari ne kuma mai kayatarwa, yayin da suke nuna cewa abinci mai mai mai yawa yana canza rikodin don ladan abinci a cikin sel ɗaya a cikin hypothalamus na gefe. Haka kuma, yanzu mun ga cewa cin abinci mai yawan kitse yana canza yanayin hypothalamus na gefe ta hanyar hana mayar da martani na jijiyoyin su don haka ya raunana “birki” na cin abinci. A takaice dai, cin abinci mai kitse na iya canza kwakwalwar ku don inganta yawan cin abinci.